Skip to main content

UbiTools Overview

UbiTools is the compute layer of the UniBio Intelligence platform. It packages best-in-class antibody and protein engineering models behind a consistent interface, exposed as an MCP server at https://mcp.tools.unibiointelligence.com/mcp.

What it can do

CapabilityModels
Antibody numbering and CDR identificationAbNumber (IMGT, Kabat, Chothia, Martin)
Antibody humanizationBioPhi (Sapiens, germline grafting)
Antibody and nanobody structure predictionImmuneBuilder, ABodyBuilder3
Antibody inverse foldingAntiFold
Antibody CDR design and affinity optimizationdyMEAN
Antibody developability assessmentDeepViscosity, Aggrescan3D, AbNumber humanness
General protein structure designRFdiffusion, Genie3
Protein binder designBoltzGen, RFantibody
Sequence design from backboneProteinMPNN
Antibody database searchKASearch (Observed Antibody Space)
Protein embeddingsAbLang2, SaProt

Authentication

UbiTools requires authentication. MCP clients handle the OAuth consent flow automatically on first connect. See Connect UbiTools to an MCP client.

Job lifecycle

Most UbiTools operations are long-running. Tools block until completion and return final results — there is no separate polling step at the MCP layer. Expect runtimes from a few seconds (numbering, CDR identification) to several minutes (BoltzGen binder design, RFdiffusion).

Results are retained for 7 days, then deleted.

Next steps